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Hôpital Louis Mourier

Gastroesophageal Reflux After Sleeve Gastrectomy a Prospective Mechanistic Study:

Coupaye M, Gorbatchef C, Calabrese D, Sami O, Msika S, Coffin B, Ledoux S. Obes Surg. 2017 Oct 9. doi: 10.1007/s11695-017-2942-9. [Epub ahead of print]. PMID:28993985

Laparoscopy in the second and third trimesters of pregnancy for abdominal surgical emergencies:

Guterman S, Mandelbrot L, Keita H, Bretagnol F, Calabrese D, Msika S. J Gynecol Obstet Hum Reprod. 2017 May;46(5):417-422. doi: 10.1016/j.jogoh.2017.03.008. Epub 2017 Mar 31. PMID: 28934085

An artificial neural network to predict resting energy expenditure in obesity:

Disse E, Ledoux S, Bétry C, Caussy C, Maitrepierre C, Coupaye M, Laville M, Simon C. Clin Nutr. 2017 Sep 1. pii: S0261-5614(17)30258-3. doi: 10.1016/j.clnu.2017.07.017. [Epub ahead of print] PMID: 28893410

Long-term follow-up after bariatric surgery in a national cohort: 

Thereaux J, Lesuffleur T, Païta M, Czernichow S, Basdevant A, Msika S, Millat B, Fagot-Campagna A. Br J Surg. 2017 Sep;104(10):1362-1371. doi: 10.1002/bjs.10557. Epub 2017 Jun 28. PMID: 28657109

To What Extent Does Posthospital Discharge Chemoprophylaxis Prevent Venous Thromboembolism After Bariatric Surgery?

Results From a Nationwide Cohort of More Than 110,000 Patients.Thereaux J, Lesuffleur T, Czernichow S, Basdevant A, Msika S, Nocca D, Millat B, Fagot-Campagna A. Ann Surg. 2017 May 4. doi: 10.1097/SLA.0000000000002285. [Epub ahead of print] PMID: 28475558

CD36 Is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential:

Gao H, Volat F, Sandhow L, Galitzky J, Nguyen T, Esteve D, Åström G, Mejhert N, Ledoux S, Thalamas C, Arner P, Guillemot JC, Qian H, Rydén M, Bouloumié A. Stem Cells. 2017 Jul;35(7):1799-1814. doi: 10.1002/stem.2635. Epub 2017 May 18. PMID: 28470788

Do sleeve gastrectomy and gastric bypass influence treatment with proton pump inhibitors 4 years after surgery? A nationwide cohort:

Thereaux J, Lesuffleur T, Czernichow S, Basdevant A, Msika S, Nocca D, Millat B, Fagot-Campagna A. Surg Obes Relat Dis. 2017 Jun;13(6):951-959. doi: 10.1016/j.soard.2016.12.013. Epub 2016 Dec 23. PMID:28223087

Evaluation of incidence of cholelithiasis after bariatric surgery in subjects treated or not treated with ursodeoxycholic acid:

Coupaye M, Calabrese D, Sami O, Msika S, Ledoux S. Surg Obes Relat Dis. 2017 Apr;13(4):681-685. doi: 10.1016/j.soard.2016.11.022. Epub 2016 Dec 2. PMID:28089591

Relevance of Self-reported Behavioral Changes Before Bariatric Surgery to Predict Success After Surgery:

Ledoux S, Sami O, Breuil MC, Delapierre M, Calabrese D, Msika S, Coupaye M.Obes Surg. 2017 Jun;27(6):1453-1459. doi: 10.1007/s11695-016-2496-2.PMID:27943093

Current challenges in providing bariatric surgery in France: A nationwide study:

Czernichow S, Paita M, Nocca D, Msika S, Basdevant A, Millat B, Fagot-Campagna A. Medicine (Baltimore). 2016 Dec;95(49):e5314.PMID:27930509

Impact of Intragastric Balloon Before Laparoscopic Gastric Bypass on Patients with Super Obesity:

a Randomized Multicenter Study.Coffin B, Maunoury V, Pattou F, Hébuterne X, Schneider S, Coupaye M, Ledoux S, Iglicki F, Mion F, Robert M, Disse E, Escourrou J, Tuyeras G, Le Roux Y, Arvieux C, Pouderoux P, Huten N, Alfaiate T, Hajage D, Msika S. Obes Surg. 2017 Apr;27(4):902-909. doi: 10.1007/s11695-016-2383-x. PMID:27664095

Effect of Genotype and Previous GH Treatment on Adiposity in Adults With Prader-Willi Syndrome:

Coupaye M, Tauber M, Cuisset L, Laurier V, Bieth E, Lacorte JM, Oppert JM, Clément K, Poitou C.J Clin Endocrinol Metab. 2016 Dec;101(12):4895-4903. Epub 2016 Sep 23. PMID:27662437

Consequences of Small Intestinal Bacterial Overgrowth in Obese Patients Before and After Bariatric Surgery:

Sabate JM, Coupaye M, Ledoux S, Castel B, Msika S, Coffin B, Jouet P. Obes Surg. 2017 Mar;27(3):599-605. doi: 10.1007/s11695-016-2343-5. PMID:27576576

Malabsorption and intestinal adaptation after one anastomosis gastric bypass compared with Roux-en-Y gastric bypass in rats:

Cavin JB, Voitellier E, Cluzeaud F, Kapel N, Marmuse JP, Chevallier JM, Msika S, Bado A, Le Gall M. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G492-500. doi: 10.1152/ajpgi.00197.2016. Epub 2016 Jul 14. PMID:27418681

Determinants of Evolution of Glomerular Filtration Rate After Bariatric Surgery: a 1-Year Observational Study:

Coupaye M, Flamant M, Sami O, Calabrese D, Msika S, Bogard C, Vidal-Petiot E, Ledoux S. Obes Surg. 2017 Jan;27(1):126-133. doi: 10.1007/s11695-016-2260-7. PMID:27312348

Chevrot A, Kayem G, Lesage N, Mandelbrot L, Coupaye M, Msika S. Am J Obstet Gynecol. 2016 Jun;214(6):767-8. doi: 10.1016/j.ajog.2016.02.024. Epub 2016 Feb 13. No abstract available. PMID:26884273

Laparoscopic sleeve gastrectomy in children and adolescents with Prader-Willi Syndrome, a matched control study:

Coupaye M, Poitou C, Tauber M. Surg Obes Relat Dis. 2016 Jan;12(1):213-4. doi: 10.1016/j.soard.2015.09.015. Epub 2015 Sep 26. No abstract available. PMID:26802226

Impact of bariatric surgery on fetal growth restriction: experience of a perinatal and bariatric surgery center:

Chevrot A, Kayem G, Coupaye M, Lesage N, Msika S, Mandelbrot L. Am J Obstet Gynecol. 2016 May;214(5):655.e1-7. doi: 10.1016/j.ajog.2015.11.017. Epub 2015 Nov 25.PMID:26627725

Digestive surgical complications during pregnancy following bariatric surgery: Experience of a center for perinatology and obesity.

Chevrot A, Lesage N, Msika S, Mandelbrot L. J Gynecol Obstet Biol Reprod (Paris). 2016 Apr;45(4):372-9. doi: 10.1016/j.jgyn.2015.04.007. Epub 2015 May 21. French. PMID:26002988

Comparison of the incidence of cholelithiasis after sleeve gastrectomy and Roux-en-Y gastric bypass in obese patients: a prospective study:

Coupaye M, Castel B, Sami O, Tuyeras G, Msika S, Ledoux S. Surg Obes Relat Dis. 2015 Jul-Aug;11(4):779-84. doi: 10.1016/j.soard.2014.10.015. Epub 2014 Oct 23. PMID:25851775

Cardiovascular Changes After Gastric Bypass Surgery: Involvement of Increased Secretions of Glucagon-Like Peptide-1 and Brain Natriuretic Peptide:

Gandolfini MP, Coupaye M, Bouaziz E, Dehoux M, Hajage D, Lacorte JM, Ledoux S. Obes Surg. 2015 Oct;25(10):1933-9. doi: 10.1007/s11695-015-1643-5. PMID:25788361

Seven novel deleterious LEPR mutations found in early-onset obesity: a ΔExon6-8 shared by subjects from Reunion Island, France, suggests a founder effect:

Huvenne H, Le Beyec J, Pépin D, Alili R, Kherchiche PP, Jeannic E, Frelut ML, Lacorte JM, Nicolino M, Viard A, Laville M, Ledoux S, Tounian P, Poitou C, Dubern B, Clément K. J Clin Endocrinol Metab. 2015 May;100(5):E757-66. doi: 10.1210/jc.2015-1036. Epub 2015 Mar 9.PMID:25751111

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients:

Magalhaes I, Pingris K, Poitou C, Bessoles S, Venteclef N, Kiaf B, Beaudoin L, Da Silva J, Allatif O, Rossjohn J, Kjer-Nielsen L, McCluskey J, Ledoux S, Genser L, Torcivia A, Soudais C, Lantz O, Boitard C, Aron-Wisnewsky J, Larger E, Clément K, Lehuen A. J Clin Invest. 2015 Apr;125(4):1752-62. doi: 10.1172/JCI78941. Epub 2015 Mar 9. PMID:25751065

Human white and brite adipogenesis is supported by MSCA1 and is impaired by immune cells:

Estève D, Boulet N, Volat F, Zakaroff-Girard A, Ledoux S, Coupaye M, Decaunes P, Belles C, Gaits-Iacovoni F, Iacovoni JS, Rémaury A, Castel B, Ferrara P, Heymes C, Lafontan M, Bouloumié A, Galitzky J. Stem Cells. 2015 Apr;33(4):1277-91. doi: 10.1002/stem.1916.PMID:25523907

Metabolic and adipose tissue signatures in adults with Prader-Willi syndrome: a model of extreme adiposity:

Lacroix D, Moutel S, Coupaye M, Huvenne H, Faucher P, Pelloux V, Rouault C, Bastard JP, Cagnard N, Dubern B, Clément K, Poitou C. J Clin Endocrinol Metab. 2015 Mar;100(3):850-9. doi: 10.1210/jc.2014-3127. Epub 2014 Dec 5. PMID: 25478934

Medical, psychological and social features in a large cohort of adults with Prader-Willi syndrome: experience from a dedicated centre in France:

Laurier V, Lapeyrade A, Copet P, Demeer G, Silvie M, Bieth E, Coupaye M, Poitou C, Lorenzini F, Labrousse F, Molinas C, Tauber M, Thuilleaux D, Jauregi J. J Intellect Disabil Res. 2015 May;59(5):411-21. doi: 10.1111/jir.12140. Epub 2014 Jun 20.PMID: 24947991

Long-term evolution of nutritional deficiencies after gastric bypass: an assessment according to compliance to medical care:

Ledoux S, Calabrese D, Bogard C, Dupré T, Castel B, Msika S, Larger E, Coupaye M. Ann Surg. 2014 Jun;259(6):1104-10. doi: 10.1097/SLA.0000000000000249. PMID: 24821236

Comparison of nutritional status during the first year after sleeve gastrectomy and Roux-en-Y gastric bypass:

Coupaye M, Rivière P, Breuil MC, Castel B, Bogard C, Dupré T, Flamant M, Msika S, Ledoux S. Obes Surg. 2014 Feb;24(2):276-83. PMID:24122661

Adipose tissue angiogenesis in obesity:

Lemoine AY, Ledoux S, Larger E. Thromb Haemost. 2013 Oct;110(4):661-8. doi: 10.1160/TH13-01-0073. Epub 2013 Apr 18. Review. PMID:23595655

Microparticle increase in severe obesity: not related to metabolic syndrome and unchanged after massive weight loss:

Stepanian A, Bourguignat L, Hennou S, Coupaye M, Hajage D, Salomon L, Alessi MC, Msika S, de Prost D. Obesity (Silver Spring). 2013 Nov;21(11):2236-43. doi: 10.1002/oby.20365. Epub 2013 Jul 2. PMID: 23512861

Comparison of body composition, basal metabolic rate and metabolic outcomes of adults with Prader Willi syndrome or lesional hypothalamic disease, with primary obesity:

Lloret-Linares C, Faucher P, Coupaye M, Alili R, Green A, Basdevant A, Clément K, Poitou C. Int J Obes (Lond). 2013 Sep;37(9):1198-203. doi: 10.1038/ijo.2012.228. Epub 2013 Jan 15. PMID:23318724

Gastric leak after laparoscopic sleeve gastrectomy: early covered self-expandable stent reduces healing time:

Simon F, Siciliano I, Gillet A, Castel B, Coffin B, Msika S. Obes Surg. 2013 May;23(5):687-92. doi: 10.1007/s11695-012-0861-3. PMID:23315096

Growth hormone therapy for children and adolescents with Prader-Willi syndrome is associated with improved body composition and metabolic status in adulthood:

Coupaye M, Lorenzini F, Lloret-Linares C, Molinas C, Pinto G, Diene G, Mimoun E, Demeer G, Labrousse F, Jauregi J, Laurier V, Basdevant A, Polak M, Thuilleaux D, Tauber M, Poitou C. J Clin Endocrinol Metab. 2013 Feb;98(2):E328-35. doi: 10.1210/jc.2012-2881. Epub 2013 Jan 2. PMID: 23284006

Serum vitamin D increases with weight loss in obese subjects 6 months after Roux-en-Y gastric bypass:

Coupaye M, Breuil MC, Rivière P, Castel B, Bogard C, Dupré T, Msika S, Ledoux S. Obes Surg. 2013 Apr;23(4):486-93. doi: 10.1007/s11695-012-0813-y. PMID:23150206

Link between adipose tissue angiogenesis and fat accumulation in severely obese subjects:

Lemoine AY, Ledoux S, Quéguiner I, Caldérari S, Mechler C, Msika S, Corvol P, Larger E. J Clin Endocrinol Metab. 2012 May;97(5):E775-80. doi: 10.1210/jc.2011-2649. Epub 2012 Mar 14. PMID:22419723

Acute small bowel obstruction following laparoscopic Roux-en-Y gastric bypass during pregnancy: two different presentations:

Tuyeras G, Pappalardo E, Msika S. J Surg Case Rep. 2012 Jul 1;2012(7):1. doi: 10.1093/jscr/2012.7.1.

Pregnancy after laparoscopic bariatric surgery: comparative study of adjustable gastric banding and Roux-en-Y gastric bypass:

Facchiano E, Iannelli A, Santulli P, Mandelbrot L, Msika S. Surg Obes Relat Dis. 2012 Jul-Aug;8(4):429-33. doi: 10.1016/j.soard.2011.06.006. Epub 2011 Jun 24. PMID:21955747

Hôpital Jean Verdier

Benmohammed K, Valensi P, Nguyen MT, Benmohammed F, Benlatreche M, Benembarek K, Lezzar A. Influence of waist circumference on blood pressure status in non-obese adolescents. Int J Adolesc Med Health. 2018 Jan 15. pii: /j/ijamh.ahead-of-print/ijamh-2017-0127/ijamh-2017-0127.xml. doi: 10.1515/ijamh-2017-0127. [Epub ahead of print] PubMed PMID: 29332014.

Benmohammed K, Valensi P, Balkau B, Lezzar A. Metabolic syndrome in adolescents:

definition based on regression of IDF adult cut-off points. Public Health. 2016 Dec;141:88-94. doi: 10.1016/j.puhe.2016.09.001. Epub 2016 Oct 7. PubMed PMID: 27932021.

Chiheb S, Cosson E, Banu I, Hamo-Tchatchouang E, Cussac-Pillegand C, Nguyen MT, Valensi P. Are Obese Individuals with no Feature of Metabolic Syndrome but Increased Waist Circumference Really Healthy? A Cross Sectional Study. Exp Clin Endocrinol Diabetes. 2016 Jul;124(7):410-6. doi: 10.1055/s-0035-1569264. Epub 2016 May 24. PubMed PMID: 27219879.

Banu I, Nguyen MT, Hamo-Tchatchouang E, Cosson E, Valensi P. [Relationship between blood pressure, heart rate and cardiac autonomic dysfunction in non-diabetic obese patients]. Ann Cardiol Angeiol (Paris). 2015 Jun;64(3):139-44. doi: 10.1016/j.ancard.2015.04.021. Epub 2015 Jun 2. French. PubMed PMID:26047878.

Fysekidis M, Cosson E, Banu I, Duteil R, Cyrille C, Valensi P. Increased glycemic variability and decrease of the postprandial glucose contribution to HbA1c in obese subjects across the glycemic continuum from normal glycemia to first time diagnosed diabetes. Metabolism. 2014 Dec;63(12):1553-61. doi: 10.1016/j.metabol.2014.09.006. Epub 2014 Sep 26. PubMed PMID: 25308444.

Cosson E, Chiheb S, Cussac-Pillegand C, Banu I, Hamo-Tchatchouang E, Nguyen MT, Aout M, Charnaux N, Valensi P. Haemoglobin glycation may partly explain the discordance between HbA1c measurement and oral glucose tolerance test to diagnose dysglycaemia in overweight/obese subjects. Diabetes Metab. 2013 Apr;39(2):118-25. doi: 10.1016/j.diabet.2012.08.013. Epub 2012 Dec 4. PubMed PMID: 23219071.

Cosson E, Chiheb S, Hamo-Tchatchouang E, Nguyen MT, Aout M, Banu I, Pillegand C, Vicaut E, Valensi P. Use of clinical scores to detect dysglycaemia in overweight or obese women. Diabetes Metab. 2012 Jun;38(3):217-24. doi: 10.1016/j.diabet.2011.11.007. Epub 2012 Feb 1. PubMed PMID: 22300975.

Benmohammed K, Nguyen MT, Khensal S, Valensi P, Lezzar A. Arterial hypertension in overweight and obese Algerian adolescents: role of abdominal adiposity. Diabetes Metab. 2011 Sep;37(4):291-7. doi: 10.1016/j.diabet.2010.10.010. Epub 2011 Jan 28. PubMed PMID: 21277245.

Cosson E, Hamo-Tchatchouang E, Banu I, Nguyen MT, Chiheb S, Ba H, Valensi P. A large proportion of prediabetes and diabetes goes undiagnosed when only fasting plasma glucose and/or HbA1c are measured in overweight or obese patients. Diabetes Metab. 2010 Sep;36(4):312-8. doi: 10.1016/j.diabet.2010.02.004. PubMed PMID: 20627649.

Poghosyan T, Polliand C, Bernard K, Rizk N, Valensi P, Champault G. [Comparison of quality of life in morbidly obese patients and healthy volunteers. A prospective study using the GIQLI questionnaire]. J Chir (Paris). 2007 Mar-Apr;144(2):129-33; discussion 134. French. PubMed PMID: 17607228.

Kopelman P, Bryson A, Hickling R, Rissanen A, Rossner S, Toubro S, Valensi P. Cetilistat (ATL-962), a novel lipase inhibitor: a 12-week randomized, placebo-controlled study of weight reduction in obese patients. Int J Obes (Lond). 2007 Mar;31(3):494-9. Epub 2006 Sep 5. PubMed PMID: 16953261.

Dabiré H, Brahimi M, Hadj-Brahim F, Le Clésiau H, Attali JR, Valensi P. [Role of vagosympathetic balance in obesity-induced hypertension]. Arch Mal Coeur Vaiss. 2004 Jul-Aug;97(7-8):749-52. French. PubMed PMID: 15506059.

Guy-Grand B, Drouin P, Eschwège E, Gin H, Joubert JM, Valensi P. Effects of orlistat on obesity-related diseases – a six-month randomized trial. Diabetes Obes Metab. 2004 Sep;6(5):375-83. PubMed PMID: 15287931.

Valensi P, Pariès J, Attali JR; French Group for Research and Study of Diabetic Neuropathy. Cardiac autonomic neuropathy in diabetic patients: influence of diabetes duration, obesity, and microangiopathic complications–the French multicenter study. Metabolism. 2003 Jul;52(7):815-20. PubMed PMID: 12870154.

Brahimi M, Dabire H, Platon P, Hadj-Brahim F, Attali JR, Valensi P. [Arterial rigidity and cardiovascular vagosympathetic activity in normotensive and hypertensive obese patients and type 2 diabetics]. Arch Mal Coeur Vaiss. 2001 Aug;94(8):944-6. French. PubMed PMID: 11575237.

Valensi P, Dabire H, Brahimi M, Paries J, Platon P, Attali JR. [Relationship between vasosympathetic activity and insulin resistance in normotensive and mildly hypertensive obese patients].Arch Mal Coeur Vaiss. 2001 Aug;94(8):941-3. French. PubMed PMID: 11575236.

Doaré L, Mesangeau D, Adli H, Germack R, Perret G, Valensi P. [Hemodynamic consequences of endogenous hyperinsulinism in obese rats with lesions of the ventromedial hypothalamus]. Arch Mal Coeur Vaiss. 2000 Aug;93(8):1015-8. French. PubMed PMID: 10989748.

Valensi P, Smagghue O, Pariès J, Velayoudon P, Lormeau B, Attali JR. Impairment of skin vasoconstrictive response to sympathetic activation in obese patients: influence of rheological disorders. Metabolism. 2000 May;49(5):600-6. PubMed PMID: 10831169.

Valensi P, Paries J, Assad N, Lormeau B, Attali JR. [Insulin resistance and alteration of cardiac vagal activity in obese patients]. Arch Mal Coeur Vaiss. 1999 Aug;92(8):1101-3. French. PubMed PMID: 10486673.

Lucas D, Farez C, Bardou LG, Vaisse J, Attali JR, Valensi P. Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation. Fundam Clin Pharmacol. 1998;12(5):553-8. PubMed PMID: 9794154.

Valensi P, Lormeau B, Dabbech M, Miossec P, Pariès J, Dauchy F, Attali JR. Glucose-induced thermogenesis, inhibition of lipid oxidation rate and autonomic dysfunction in non-diabetic obese women. Int J Obes Relat Metab Disord. 1998 Jun;22(6):494-9. PubMed PMID: 9665668.

Sibony-Prat J, Paries J, Chabert M, Attali JR, Valensi P. [Alteration of cardiovascular vagosympathetic control evaluated by spectral analysis of variations of heart rate and blood pressure in obesity]. Arch Mal Coeur Vaiss. 1997 Aug;90(8):1155-8. French. PubMed PMID: 9404427.

Valensi P, Assayag M, Busby M, Pariès J, Lormeau B, Attali JR. Microalbuminuria in obese patients with or without hypertension. Int J Obes Relat Metab Disord. 1996 Jun;20(6):574-9. PubMed PMID: 8782735.

Valensi P, Derobert E, Genthon R, Riou JP. Effect of ramipril on insulin sensitivity in obese patients. Time-course study of glucose infusion rate during euglycaemic hyperinsulinaemic clamp. Diabetes Metab. 1996 Jun;22(3):197-200. PubMed PMID: 8697308.

Smagghue O, Velayoudon P, Paries J, Attali JR, Valensi P. [The Laser-Doppler microcirculation technique in the study of the orthosympathetic system in obese and non-insulin-dependent diabetic patients]. J Mal Vasc. 1996;21(5):299-302. French. PubMed PMID: 9026546.

Valensi P, Busby M, Combes ME, Attali JR. [Microalbuminuria and hypertension in obese patients]. Arch Mal Coeur Vaiss. 1992 Aug;85(8):1193-5. French. PubMed PMID: 1482258.